Advances in Health and Disease. Volume 4

Lowell T. Duncan (Editor)

Series: Advances in Health and Disease
BISAC: MED022000



Volume 10

Issue 1

Volume 2

Volume 3

Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick


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In Advances in Health and Disease. Volume 4, the authors open by reflecting on the potential advantages and challenges of the focus group technique in health services research, based on a study conducted to better understand the perceptions and experiences related to access and utilization of healthcare services for immigrants in Portugal. Later, the authors examine Parvovirus B19 (PVB19), a widespread infection that affects 1-5% of pregnant women. The authors maintain that as PVB19 infection can cause severe morbidity and mortality, it should be part of the routine work up of complicated pregnancies, especially when fetal hydrops is suspected. This book also summarizes the evidence on propensity for TDM in anti-TNF therapy to guide interventions at therapeutic failure, while present data do not support the routine use of proactive TDM in everyday clinical practice. The authors maintain that the use of statins is necessary for the prevention and treatment of atherosclerosis, and the criteria for assessing their hypolipidemic effect are clearly defined. Depending on the severity of experimental hyperlipoproteinemia, oral administration of atorvastatin may have a different effect on the overall activity of MMPs in the serum of mice. The following chapter discusses how employing focus groups provided the opportunity to 1) check cultural assumptions, 2) assess and prioritize areas of greatest perceived need, 3) tailor campaigns and outreach to the key values and beliefs of the population of focus, and 4) understand and capitalize on social media and other communication favored by Hispanic young adults in a minority serving institution in order to reduce HIV related health disparities. Next, Congenital Hypothyroidism is examined as the most common endocrine disorder in childhood. In the last years the decrease of the TSH recall threshold has led to an increased of mild forms with in situ glands at the first diagnosis. As such, the re-evaluation of the diagnosis has become an important procedure to distinguish transient forms from permanent ones. Three types of Burkitt’s Lymphoma are also examined, including Endemic (African), Sporadic (non-African) and HIV-associated per WHO classification. Compared to the endemic type which is commonly associated with EBV infection, the incidence of EBV is lower in the other two types (20% in sporadic and 30- 40% in HIV patients). After which, end stage renal disease is examined in the same manner, reviewing the diagnosis, management and consequences. In a separate study, an integrated mixed method approach was used in 5 coastal communities in Tongatapu, Tonga, where some community members had their health and well-being affected by climate change and some did not. Results indicated that physical, mental and spiritual aspects of well-being were affected by climate change and that people were eager to see the implementation of strategies to improve their health and restore their mental well-being. The concluding study aimed to verify the influence of different motivational interventions for oral hygiene autonomy promotion on the biofilm control in individuals with special needs. The data suggest that motivational activities can be developed to promote autonomy in other aspects of general health, resulting in the improvement of the quality of life of individuals with special needs.


Chapter 1. The Potential of Focus Groups in Health Research: A Study on Immigrants’ Access to and Utilization of Health Services
(Sónia Dias, PhD and Ana Gama, Global Health and Tropical Medicine, GHTM, Instituto de Higiene e Medicina Tropical, IHMT, Universidade Nova de Lisboa, UNL. Lisboa, Portugal)

Chapter 2. Parvovirus B19 (PVB19) in Pregnancy: The Impact of a Partially Neglected Problem
(Asher Ornoy, MD and Zivanit Ergaz, MD, Laboratory of Teratology, Department of Medical Neurobiology, Canada Israel Institute for Medical Research, Hebrew University Hadassah Medical School, Jerusalem, Israel, and others)

Chapter 3. The Role of Therapeutic Drug Monitoring for TNF Inhibitors in IBD: Selected Cases or Everyday Practice?
(Lorant Gonczi, MD, Zsuzsanna Vegh, MD, Zsuzsanna Kurti, MD, Peter L. Lakatos MD, Semmelweis University, First Department of Internal Medicine, Budapest, Hungary, and others)

Chapter 4. Atorvastatin: Prevention and Treatment of Dyslipidemia in Clinical and Experimental Medicine
(Korolenko T.A., Johnston T.P., Cherkanova M.S., Goncharova N.V., Vavilin V.A., Shintyapina A.B., Bgatova N.P., and Kaledin V.I., Institute of Physiology and Basic Medicine, Novosibirsk, Russia, and others)

Chapter 5. Focus Groups in Health Disparities Research: Lessons Learned from an HIV Prevention Program with Hispanic Young Adults
(Sofia Fernandez, PhD, Rachel Clarke, PhD, Melissa Howard, PhD, Staci Morris, PsyD, Michelle Hospital, PhD, and Eric F. Wagner, PhD, FIU-BRIDGE, Florida International University, Miami, FL, USA)

Chapter 6. Congenital Hypothyroidism (CH): The Re-Evaluation of Diagnosis in CH Patients with in Situ Glands Identified by Newborn Screening
(R. Ortolano, M. Bitelli, F. Baronio, and A. Cassio, Department of Women, Child Health and Urologic Diseases, Pediatric Unit, S.Orsola-Malpighi University Hospital, Bologna, Italy, and others)

Chapter 7. Burkitt’s Lymphoma: Etioloy, Pathology, Prognosis and Treatment
(Dr. Seema Naik, Penn State Cancer Institute, Hershey, Pennsylvania, USA)

Chapter 8. Challenges of Blood Pressure Management in Patients with End-Stage Renal Disease
(Shan Shan Chen and Zhi Qiang Xu, Nephrology Division, Department of Medicine at the University of New Mexico School of Medicine, Albuquerque, NM, USA)

Chapter 9. Improving Health and Well-being Through Climate Change Adaptation
(Peni H. Havea, Sarah L. Hemstock, PhD, and Helene Jacot Des Combes, PhD, PaCE-SD, The University of the South Pacific, Suva, Fiji)

Chapter 10. Oral Hygiene Autonomy Promotion in Individuals with Special Needs
(Maria Cristina Duarte Ferreira, PhD, Bruna Sumaya Souza Pinto, Manuela Costa Andrade Silva, Sucena Matuk Long, PhD, Renata Pilli Joias, PhD, Erika Josgrilberg Guimarães, PhD, Professor of Pediatric Dentistry and Public Health Departments of Health and Medicine Science School of Universidade Metodista de São Paulo, Brazil, and others)


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