Advances in Health and Disease. Volume 17


Lowell T. Duncan (Editor)

Series: Advances in Health and Disease
BISAC: MED022090

Obesity worldwide represents a public health problem, compromising life expectancy in children and adolescents, and has been associated with mortality and a higher risk of developing non-alcoholic fatty liver disease. Advances in Health and Disease. Volume 17 investigates the association of adiponectin concentration with metabolic and inflammatory profiles of adolescents with obesity and diagnosis of non-alcoholic fatty liver disease.

Non-alcoholic fatty liver disease is considered the hepatic manifestation of obesity, metabolic syndrome and type 2 diabetes mellitus, where the main toxic mediators in this condition are free fatty acids, triglycerides and cholesterol accumulation.
In the context of liver transplantation, recipient hemodynamic stability is necessary for its reliable measurement. As such, the authors discuss how the plasma disappearance rate of indocyanine green has shown usefulness in different pathologies.

The authors go on to discuss spondylosis, a defect in the pars interarticularis of the neural arch, which is a common cause of back pain. The management principles of symptomatic spondylolisthesis have remained consistent over the decades; however, there is a constant evolution in the understanding of the biomechanics of spondylolisthesis, reduction techniques, and fusion modalities.

The symptoms, diagnosis and treatment of degenerative spondylolisthesis and isthmic spondylolisthesis in the lumbar spine are discussed.

Following this, the authors review the current understanding of delirium pathophysiology, examining the current evidence-based guidelines regarding the screening, prevention and treatment of delirium as relevant to the bedside clinician.

This compilation also explores awake craniotomy, a neurosurgical approach performed with the patient awake during the procedure. This approach is increasingly widespread for the surgical treatment of supratentorial cortical lesions and, in particular, for the excision of lesions near or within the motor or language areas.

The penultimate chapter examines age-related macular degeneration, the leading cause of irreversible visual function decrease among elderly individuals in developed countries. Most of the patients are affected by the atrophic, non-exudative form that is characterized by the occurrence of progressive atrophy of the retinal pigment epithelium and photoreceptors.

The final study focuses on Clostridium difficile infections associated with high incidence, mortality, and healthcare costs. C. difficile infections are mainly linked to the use of wide-spectrum antibiotics that disrupt the intestinal microbiota equilibrium.
(Imprint: Nova Medicine and Health)

Table of Contents

Table of Contents


Chapter 1. Non-Alcoholic Fatty Liver Disease in Adolescents with Obesity: The Role of Adiponectin
(Sofia Emanuelle de Castro Ferreira Vicente, Raquel Munhoz da Silveira Campos, Aline de Piano Ganen and Ana R. Dâmaso, Faculdade Anhanguera, Campus Baixada Santista, Universidade Federal de São Paulo, São Paulo, Brazil, and others)

Chapter 2. Non-Alcoholic Fatty Liver Disease Physiopathology, Diagnostic Approach and Management Strategy
(Nicolás Salva-Pastor, Norberto C. Chávez-Tapia, Misael Uribe and Natalia Nuño-Lámbarri, Traslational Research Unit, Medica Sur Clinic and Foundation, Mexico City, Mexico, and others)

Chapter 3. Properties and Application of Indocyanine Green in Liver Transplantation
(Pablo Lozano, MD, PhD, Cristina Julia Lisbona, MD, PhD, Lorena Martín, MD, Luis Olmedilla, MD, PhD, and Jose Ángel López Baena, MD, PhD, Liver Transplant Unit, Hospital Universitario Gregorio Marañón de Madrid, Madrid, Spain, and others)

Chapter 4. Spondylolisthesis: Symptoms and Diagnosis
(Vaibhav Jain and Virendra K. Verma, Department of Orthopaedics, AIIMS Bhopal, India)

Chapter 5. Lumbar Spondylolisthesis: Symptoms, Diagnosis and Conservative Treatment
(Emel Ece Özcan-Ekşi, MD, and Sibel Demir-Deviren, MD, Deparment of Physical Medicine and Rehabilitation, Bahçeşehir University School of Medicine, Istanbul Turkey, and the Department of Orthopaedic Surgery, University of California, San Francisco,  CA, USA)

Chapter 6. Delirium in the Surgical Patient
(Ryan M. Landis, MD, Bishwajit Bhattacharya, MD, Department of General Surgery, Trauma, and Surgical Critical Care, Yale School of Medicine, New Haven, CT, US)

Chapter 7. Conduct of Anesthesia in Awake Craniotomy for Excision of Lesions Located within or near Eloquent Language Areas
(Marco Cascella, MD, and Domenico Carbone, MD, Division of Anesthesia and Pain Management, Department of Supportive Care, Istituto Nazionale Tumori Fondazione G. Pascale IRCSS, Naples, Italy, and others)

Chapter 8. Measuring Visual Function by Reading Speed and Low Luminance Visual Acuity in the Era of Age-Related Macular Degeneration
(Clara Gonzalez-Urueña, Marta Fernandez-Muñoz, MD, and Javier A. Montero-Moreno, MD, Health Sciences Institute of Castilla and Leon, Valladolid, Spain, and others)

Chapter 9. Clostridium Difficile Infection
(Asem Shehabi and Eman Badran, University of Jordan, Amman, Jordan)


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