Advances in Genetics Research. Volume 22

$250.00

Kevin V. Urbano (Editor)

Series: Advances in Genetics Research
BISAC: SCI029000

This volume includes five chapters, each detailing recent advances in genetics research. Chapter one discusses how germline predisposition diseases are associated with a dramatically increased risk of developing myelodysplastic syndrome (MDS), acute myeloid leukemia (AML), and other malignancies.  Chapter two explores how myeloid neoplasms originate from hematopoietic stem cells through the process known as clonal hematopoiesis. Chapter three summarizes current knowledge on the epigenetic changes induced by monoterpenes, providing an overview as well as recent findings regarding the topic of epigenetics. In chapter four, the authors investigate both the benefits and negative effects of genetic screening. Chapter five analyses the sequenced genomes of M. tuberculosis and the rearrangements of genes from the PE-PGRS family.

Table of Contents

Preface

Chapter 1. Germline Genetic Mutations in the Predisposition to Myelodysplastic Syndrome and Acute Myeloid Leukemia
Ota Fuchs
Institute of Hematology and Blood Transfusion, Prague, Czech Republic

Chapter 2. Clonal Hematopoiesis as a Predictor of Subsequent Myeloid Cancers
Ota Fuchs
Institute of Hematology and Blood Transfusion, Prague, Czech Republic

Chapter 3. The Epigenetic of Monoterpenes in the Pathological Context
Fernando Augusto de Oliveira Ganzella¹, Gabriela Casani Cardoso², Regiane da Cunha², Vanessa Crocetti², Andrea Emilia Marques Stinghen¹,², PhD, and Edneia Amancio de Souza Ramos¹,², PhD
¹Department of Basic Pathology, Universidade Federal do Paraná (UFPR), Curitiba, Paraná, Brazil
²Post-graduate Program of Microbiology, Parasitology and Pathology, UFPR

Chapter 4. The Right to Know and the Right Not to Know: Shadows and Lights of Genetic Screening
Ciro Comparetto¹ and Franco Borruto²
¹Department of Obstetrics and Gynecology, San Paolo Private Clinic, Pistoia, Italy
²Consultant in Health Policy of the Government, Department of Social Affairs and Health, Monaco

Chapter 5. Analysis of Variation in the PE_PGRS Genes of Mycobacterium Tuberculosis and Mechanisms of Spontaneous Mutations
Veranika Slizen¹, PhD, Larisa K. Surkova², Dr.Sc., Professor, and Leonid P. Titov³, Dr.Sc., Professor ¹Republican Scientific and Practical Center of Pulmonology and Phthisiology, Minsk, Republic of Belarus
²Arak University of Medical Sciences, Arak, Iran
³Republican Scientific and Practical Center of Epidemiology and Microbiology, Minsk, Republic of Belarus

Index

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