Advances in Drug Resistance Research


Christudas Morais, PhD (Editor)
Centre for Kidney Disease Research, School of Medicine,The University of Queensland, Translational Research Institute, Queensland, Australia

Series: Public Health in the 21st Century
BISAC: MED058170

Table of Contents

Drug resistance continues to be a major problem in the effective treatment of many diseases. Resistance to chemotherapy, whether intrinsic or extrinsic, is the result of at least three well defined mechanisms: prevention of the interaction of drug with the target, decreased intracellular concentration of the drug due to an increased efflux or a decreased influx, and enzymatic modification or destruction of the drug. With the advancement in technology, the molecular mechanisms of drug resistance have been unravelling at a rapid rate.

This book is a timely review of such advances in drug resistance research. The nine chapters of this book, written by a group of clinicians and scientists, elegantly summarises recent advances in our understanding of this important clinical problem with emphasis on cisplatin, fibroblasts, natural compounds, erythropoiesis-stimulating agents, prostate cancer and kidney cancer. This book will be an important contribution to science, and an invaluable tool for researchers who are interested in drug resistance. (Imprint: Nova Biomedical )



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