Advances in Chemistry Research. Volume 54


James C. Taylor (Editor)

Series: Advances in Chemistry Research
BISAC: SCI013000

The first chapter of Advances in Chemistry Research. Volume 54 investigates the structure-function relationships of glycans. A recent structural analysis of oligomannose glycans, based on biophysical methods (including solution nuclear magnetic resonance and X-ray crystallographic analyses) are presented and discussed.

A summary of the history, clinical uses, and pharmacokinetics of polyethylene glycol interferon are presented. Important features regarding its clinical efficacy in combination with new antiviral agents like ribavirin, telaprevir, entecavir, tenofovir, adefovir, sofosbuvir and ledipasvir are also discussed.

The fluorescence properties of anthracene based ligands are proposed to be suitable to design sensors for cations as well as anions. Some of the complexes of anthracene-based ligands are reported to have potential for light-emitting devices.

Various quantum chemical properties, dipole moments, bond lengths, charges, total electronic energies, the highest occupied and lowest unoccupied molecular orbital energies and the interfrontier molecular orbital energy gap values are obtained and compared.

An empirical equation is derived for calculating the free formaldehyde concentration in alcohol–formaldehyde systems at various temperatures and total formaldehyde concentrations, as well as an equation for evaluating solvent concentrations.

In the final study, the authors exploit the intense fluorescence behavior of luminol for a quantitative understanding of hydrogen bonding behavior and its interaction with several biological media, with the help of steady state and time-resolved measurements as well as density functional theory calculations. (Imprint: Nova)

Table of Contents

Table of Contents


Chapter 1. Mannose as a Component of Glycans: Structure, Dynamics and Interaction
(Yoshiki Yamaguchi, and Jun Uzawa, Structural Glycobiology Team, RIKEN, Wako, Saitama, Japan)

Chapter 2. PEGylation of a-Interferon: Biochemical, Clinical, Analytical and Stability Aspects
(Adeel Arsalan, PhD, Mirza Tasawwar Baig, PhD, Kiran Qadeer, PhD, Muhammad Ibrahim Sial, and Iqbal Ahmad, PhD, Faculty of Pharmacy, Ziauddin University, Karachi, Pakistan, and Baqai Institute of Pharmaceutical Sciences, Baqai Medical University, Karachi, Pakistan)

Chapter 3. Anthracene Based Ligands: Synthesis and Applications
(Pooja Dubey, Alpesh Kumar Sharma, and Ajai Kumar Singh, Department of Chemistry, Indian Institute of Technology, Delhi, New Delhi, India)

Chapter 4. Effect of Centric Germanium Perturbation on Anthracene
(Lemi Türker, Middle East Technical University, Department of Chemistry, Çankaya/Ankara, Turkey)

Chapter 5. Solutions of Formaldehyde in Water and Alcohols
(Michael M. Silaev, Faculty Chemistry, Lomonosov Moscow State University, Vorobievy Gory, Moscow, Russia)

Chapter 6. Application of Luminol as Solvatochromic Probe and Fluorescent Biomarker for Heterogeneous Media
(N. Shaemningwar Moyon, Imocha Rajkumar Singh, Mostofa Ataur Rohman, Prayasee Baruah, Vikash Kumar Sonu, and Sivaprasad Mitra, Center for Advanced Studies, Department of Chemistry, North-Eastern Hill University, Shillong, India)


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