Acetate: Versatile Building Block of Biology and Chemistry


David A. Sanders, PhD (Editor)
Markey Center for Structural Biology, Department of Biological Sciences, Purdue University, West Lafayette, IN, USA

Series: Chemistry Research and Applications
BISAC: SCI007000

Acetic acid and its conjugate base acetate are amazing molecules. The combination of a methyl group and a carboxylic acid/carboxylate makes acetic acid/acetate the primordium of complex organic molecules. Acetic acid is uncommon among common biological carbon sources besides gases in that it can freely diffuse across membranes.

The central role of acetate in the global carbon cycle, and the origin and evolution of life on earth are expertly portrayed by Ferry. Fermentation reduces biomass predominantly to acetate. Acetate is the metabolic currency between the bacteria and archaea domains of life. It is said that two-thirds of the methane produced in the biosphere is derived from acetate. An “energy first” hypothesis that builds on the chemoautotrophic origin of life proposal that highlights the central role of acetate thioseters is advanced.

This book spans from the origin of life to the latest developments in biology and chemistry. Its chapters elucidate how the versatile acetate, and its derivatives and partners, are critical to the metabolism, the global carbon cycle, greenhouse gas generation and climate change, among other things. (Imprint: Nova)



Table of Contents


Chapter 1. Acetate: A Key Intermediate during the Anaerobic Degradation of Organic Matter
(James G. Ferry, Department of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA, USA)

Chapter 2. Atomic Structure of a Hyperthermophilic Acetate Kinase
(Soma Mukhopadhyay, Thomas Hansen, Peter Schönheit, Miriam S. Hasson and David Avram Sanders, Department of Biological Sciences, Purdue University, West Lafayette, IN, USA, and others)

Chapter 3. HATs, HDACs and the Regulation of Cellular Processes
(Faeze Saatchi and Ann L. Kirchmaier, Department of Biochemistry,
Purdue University, West Lafayette, IN, USA)

Chapter 4. [11C]Acetate for Positron Emission Tomography Imaging
(Melissa E. Rodnick, Adam C. Runkle, Ryan Littich and Peter J. H. Scott, Department of Radiology, University of Michigan Medical School, Ann Arbor, MI, USA)

Chapter 5. Colloidal and Surfactant Properties of Poly (Vinyl Acetate-Co-Vinyl Alcohol) Copolymers
(L.I. Atanase and G. Riess, Laboratoire de Photochimie et d’Ingénierie Macromoléculaires (LPIM), Ecole Nationale Supérieure de Chimie de Mulhouse (ENSCMu), University of Haute Alsace, Cedex, France)

Chapter 6. Production of Biodiesel through Interesterification of Triglycerides with Methyl Acetate
(Abraham Casas, María Jesús Ramos and Ángel Pérez, Department of Chemical Engineering, Institute for Chemical and Environmental Technologies (ITQUIMA) University of Castilla-La Mancha Avd. Camilo, Ciudad Real, Spain)

Chapter 7. Structure Formation of Powder Cellulose Esters and Ethers in the Vapors of Specific Liquids
(A.B. Shipovskaya, Chernyshevsky Saratov State University, Saratov, Russian Federation)


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