A Multifactorial Approach to the Blood Pressure Control. The Role of the Asymmetrical Organization of the Nervous System

M Ramírez, I Banegas, AB Segarra, R Wangesteen, M de Gasparo, F Vives, F Alba, M Ruiz-Bailen and I Prieto
Unit of Physiology, Department of Health Sciences, University of Jaén, Spain, and others

Series: Human Anatomy and Physiology
BISAC: MED005000

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Volume 10

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Special issue: Resilience in breaking the cycle of children’s environmental health disparities
Edited by I Leslie Rubin, Robert J Geller, Abby Mutic, Benjamin A Gitterman, Nathan Mutic, Wayne Garfinkel, Claire D Coles, Kurt Martinuzzi, and Joav Merrick

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It is well-known that the renin-angiotensin system (RAS) participates in the regulation of blood pressure (BP) through the binding of Ang II to the AT1 receptor, other multiple factors of this and additional systems interact together to maintain the BP in physiologic conditions. The imbalance between these factors will lead to alterations of BP. Therefore, instead of studying isolated factors controlling BP, it is indicated to investigate the equilibrium or interaction between factors with opposite effects. This book considers the spatial pattern of aminopeptidase activities in normotensive and spontaneously hypertensive rats, the variations in activity in the brain and in plasma after unilateral lesions and the consequences of those lesions on nitric oxide concentration and blood pressure level. The importance of the central/peripheral asymmetries is discussed in a bilateral perspective. (Imprint: Nova)

Abstract

1. Introduction

2. Brain Asymmetry and Cardiovascular Control

3. Role of Nitric Oxide in Blood Pressure Control. Interaction with the Renin-Angiotensin System

4. Role of Dopamine in Blood Pressure Control. Interaction with the Renin-Angiotensin System

5. New Insights on the Role of the Asymmetrical Organization of the Nervous System in the Control of Blood Pressure

6. Concluding Remarks

Acknowledgments

References

Index

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