A Closer Look at Phenanthroline

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William Amies (Editor)

Series: Chemistry Research and Applications
BISAC: SCI013040

1,10-phenanthroline is a heterocycle consisting of three fused rings, with two pyridines fused on a central benzene. The two nitrogen atoms can bind metals using their lone pairs, making it a strong donor.
In this compilation, the interaction between the essential element -iron, and the phenanthroline ligand is examined. A short review of the iron biochemistry including absorption, biodistribution and biomineralization of the element in the human body is provided.
The anti-parasitary properties of phenanthroline in its coordination chemistry with ruthenium are also described, highlighting the biological and medicinal significance of the differences in the physico- chemical properties of these ligands on the activity of the resulting complexes.
(Imprint: Novinka)

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Table of Contents

Preface

Chapter 1. Phenanthroline and Its Molybdenum Complexes
(Adrià Gil and Maria José Calhorda, Biosystems and Integrative Sciences Institute, Faculdade de Ciências, Universidade de Lisboa, Campo Grande, Lisboa, Portugal, and others)

Chapter 2. Iron Phenanthroline Complexes: Speciation, Structure and Potential Medicinal Activity
(Lino Hernández, Edgar Del Carpio, Waleska Madden, Giuseppe Lubes, Mary Lorena Araujo and Vito Lubes, Laboratorio de Equilibrios en Solución, Departamento de Química, Universidad Simón Bolívar, Caracas, Venezuela, and others)

Chapter 3. Ruthenophenanthroline Complexes Active against Tripanosomids
(Susana Santos Braga, Karyna Lysenko and Nádia E. Santos, LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, Aveiro, Portugal)

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