A Closer Look at Membrane Proteins


Tristan B. Møller (Editor)

Series: Cell Biology Research Progress

A Closer Look at Membrane Proteins opens with a description of the insulin-like growth factor system, with focus on the insulin-like growth factor receptors and functions associated with them. The data on membrane proteins, their N–glycome and oxidation status id related to the authors’ findings on the receptors in different physiological and pathological conditions, such as normal and abnormal tissue growth and development.

Next, a review of the current methods used to prepare and study membrane proteins is presented, with focus on large scale simulations and special emphasis on scalable parallel methods.

In closing, commandments surrounding integral membrane protein expression and purification, integral membrane protein biochemistry, integral membrane protein functionality studies and integral membrane protein high-resolution structures are described.

Table of Contents

Table of Contents


Chapter 1. Bitter–Sweet Story of the IGF Receptors in Cell (Mal)Functioning
(Dragana Robajac, Miloš Šunderić, Nikola Gligorijević and Olgica Nedić, Institute for the Application of Nuclear Energy [INEP], University of Belgrade, Belgrade, Serbia)

Chapter 2. Simulating Membrane Proteins
(N. K. Roy, ITS-Research Computing, Northeastern University, Boston, MA, US, and others)

Chapter 3. The Commandments of Studying Integral Membrane Proteins
(Raymond J. Turner, Department of Biological Sciences, University of Calgary, Calgary, AB, Canada)


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