A Closer Look at Glycation: A Potential Hotspot for Age-Related Complications and Diseases


Dr. Nadeem Ahmad Ansari, PhD (Editor) – Department of Biotechnology, Faculty of Engineering and Technology, KMC Language University, Lucknow, India

Series: Biochemistry Research Trends

BISAC: SCI013010

This well-planned, logically structured and user-friendly book provides a useful insight into the world of non-enzymatic glycation from its early stages to an advanced level, with an eye on glycating agents, their enhancers and inhibitors. All chapters are of equal interest but the chapters on dietary AGEs and effects of AGEs on bone cells provide novelty in the area of glycation. These chapters also describe characterization of the glycation and its role in different types of age-related complications and diseases. A chapter on synthetic and plant-based natural inhibitors of glycation is also presented.

Written by a team of experts, this book makes the readers aware of the glycation process in various diseases and complications and creates enthusiasm in teaching key lessons to students of life and medical sciences. With the use of tables, figures and references, and a concise overview of the glycation mechanism and its inhibition on a single platform, this book is ideally suited as a resource for research and teaching purposes as well as contributes to knowledge of glycation inhibitors for controlling disease complications.



Table of Contents


Chapter 1. A Study on the Role of Glycated Proteins in Age-Related Diseases and Their Potential to Become a Novel Biomarker for Early Diagnosis of Diseases
(Nadeem A. Ansari, PhD – Department of Biotechnology, Faculty of Engineering and Technology, KMC Language University, India)

Chapter 2. The Effects of Glycation on Serum Albumins
(Atanu Singha Roy, Sharat Sarmah and Sourav Das – Department of Chemistry, National Institute of Technology Meghalaya, Shillong, Meghalaya)

Chapter 3. Enhancing Effect of L-Lysine on Glycation of Histone H1 and Bovine Serum Albumin In Vitro
(Yordan Handzhiyski, Rositsa Tsekovska, Kiril Kirilov, Toshimitsu Niwa, Ivan Ivanov, and Roumyana Mironova – Department of Gene Regulation, Institute of Molecular Biology “Roumen Tsanev”, Bulgarian Academy of Sciences, Sofia, Bulgaria, et al.)

Chapter 4. Dietary Advanced Glycation Endproducts: An Increasing Concern
(Gengjun Chen, J. Scott Smith – Department of Grain Science and Industry, Kansas State University, Manhattan, KS, USA, et al.)

Chapter 5. The Effects of Advanced Gycation Endproducts (AGEs) on Bone Biomechanics and Remodeling
(Xiao Yang, Lian-wen Sun, Xiaodu Wang – Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, China, et al.)

Chapter 6. Advanced Glycation Endproducts: Their Role in Aging, Diseases, and Forensic Science
(Sara Casado-Zapico – International Forensic Research Institute, Florida International University, Miami, Florida; Department of Anthropology, NMNH, Smithsonian Institution, Washington, DC,
Cassandra M. DeGaglia – Department of Anthropology, NMNH, Smithsonian Institution, Washington, DC)

Chapter 7. Potential Inhibitory Effects of Plant and Cyanobacteria-Derived Natural Products on Advanced Glycation End-Product Formation
(Rungaroon Waditee-Sirisattha, Masaki Honda, Takashi Hibino and Hakuto Kageyama – Department of Microbiology, Faculty of Science, Chulalongkorn University, Pathumwan, Bangkok, Thailand, et al.)

Chapter 8. Repurposing Drugs for the Inhibition of Advanced Glycation Endproducts Formation: A Computational Study of the Chemical Reactivity Properties of the Met-Enkephalin Neurotransmitter Peptide by Means of Conceptual DFT
(Norma Flores-Holguín, Juan Frau and Daniel Glossman-Mitnik – Laboratorio Virtual NANOCOSMOS, Departamento de Medio Ambiente y Energía, Centro de Investigación en Materiales Avanzados, Mexico, et al.)




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