A Closer Look at Actinomycetes


A. A. Mohamed Hatha (Editor)
Professor, Fulbright Scholar, Dept. of Marine Biology, Microbiology & Biochemistry, School of Marine Sciences, Cochin University of Science and Technology, Cochin, Kerala, India

P. Lakshmanaperumalsamy (Editor)

Series: Bacteriology Research Developments
BISAC: SCI006000

Actinomycetes are a versatile group of Gram positive bacteria widely distributed in the terrestrial and aquatic environments. The specialty of the actinomycetes is that they have a mycelial appearance unlike most bacteria. This group of bacteria is well known for their ability to produce a range of bioactive molecules, including antibiotics and various kinds of enzymes. As they are known for their ability to produce various antibiotics, the actinomycetes are widely explored by various research groups in search of novel drug molecules. Since the cultivation and maintenance of actinobacteria are not that easy as in the case of other bacteria, they are rather underexplored.

With the frequent emergence of multidrug resistant bacteria, which are outpacing the discovery of new antibiotics, there is a renewed interest in actinomycetes from special habitats such as extreme habitats in the marine environment, salt pans, geothermal springs, permanently frozen polar environments etc. Endophytic actinomycetes are also attracting the attention of current researchers in this field. This book titled “A Closer Look at Actinomycetes” is a compilation of articles which deals with interesting topics such as “actinomycetes as microbial drug factories”, endophytic fungi from special habitats of Pakistan as well as strategies for exploration of actinomycetes diversity and the taxonomy of actinomycetes should be of great interest to those who are interested in Actinomycetes research. People with interest in general microbiology will also find it an interesting read.
(Imprint: Nova)

Table of Contents

Table of Contents


Chapter 1. Actinomycetes: Microbial Drug Factory
(S. Aruna Sharmili, Jayashree Shanmugam and Mayakkannan Gopal, Department of Biotechnology, Stella Maris College [Autonomous], Chennai, Tamilnadu, India, and others)

Chapter 2. Endophytic Actinomycetes in Indo-Pak Medicinal Plants Leading to New Trends in Drug Discovery
(Rabia Tanvir, Ali Ahmad Sheikh and Aqeel Javeed, University Diagnostic Lab, Department of Microbiology, University of Veterinary and Animal Sciences, Lahore, Punjab, Pakistan, and others)

Chapter 3. Taxonomic Diversity and Applications of Secondary Metabolites of Amycolaptosis
(Pawina Kanchanasin and Somboon Tanasupawat, Department of Biochemistry and Microbiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand)

Chapter 4. Marine Actinomycetes as Rich Source of Novel Therapeutics for Cancer Therapy
(K. G. K. Deepak, Rama Rao Malla, Department of Biochemistry and Bioinformatics, GITAM Institute of Science, Visakhapatnam, Andhra Pradesh, India)

Chapter 5. Streptomyces: Distribution, Biocontrol and Plant Growth Promoting Activity
(Nisachon Tedsree and Somboon Tanasupawat, Department of Agricultural Technology, Faculty of Science and Arts, Burapha University, Chanthaburi Campus, Chanthaburi, Thailand, and others)

Chapter 6. Diversity and Metabolites of Endophytic Actinomycetes from Plant Roots
(Nattakorn Kuncharoen and Somboon Tanasupawat, Department of Biochemistry and Microbiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand)

Chapter 7. Metabolic Profiling of <i>Streptomyces</i> sp. Strain 51 for Detection of Bioactive Compounds
(Prateek Kumar, Aditi Kundu, Renu Solanki, Munendra Kumar and Monisha Khanna Kapur, Microbial Technology Lab, Acharya Narendra Dev College, University of Delhi, New Delhi, India, and others)

Chapter 8. Phenotypic and Genotypic Characterization of Bioactive Actinomycetes (Actinomycetales) from Tropical Wetland Ecosystem
(Maya George, Anas Abdul Azis, C. Jasmin, K. M. Mujeeb Rahiman and A. A. Mohamed Hatha, Department of Zoology, Alphonsa College Pala, Kottayam, India, and others)

Chapter 9. Actinomycetes: Taxonomy, Genomic Approach and Applications
(Nattakorn Kuncharoen, Wongsakorn Phongsopitanun and Somboon Tanasupawat, Department of Biochemistry and Microbiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand, and others)



“The actinomycetes play a key role in different environmental processes which are mediated by their ability to produce a wide range of metabolites. While recognized as a source of antibacterial agents, the potential applicability of actinomycetal metabolites is immense, varying from agricultural use as plant growth promoter to possible applications in cancer therapy. <I>A Closer Look at Actinomycetes</I> explores this fascinating and amazing bacterial genus providing a comprehensive approach to these micro-organisms and their metabolites.” <B>- Joaquim Ruiz, Researcher,Universidad Científica del Sur, Lima, Peru</B>

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