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Quick ViewTerpenoids represent the largest and most widely distributed class of natural, high-value chemicals, comprising more than 55,000 distinct molecules. Besides the wide range of biological properties, these natural compounds have found significant commercial value as pharmaceuticals, flavours and fragrances, commodity chemicals, and, more recently, as potential biofuels. Squalene is a natural lipid belonging to the…
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Quick ViewAdvances in biosensors have improved biomarker discovery, affinity receptor design, detection of infectious microorganism and disease diagnostics due to close interaction of nanotechnology with other technologies which play a critical role for the future of biosensors and health care. Biosensing technology is a fascinating field which provides reliable, rapid and sensitive platforms for specific and…
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Quick ViewThis book is about humic and fulvic acids, two types of organic substances which are increasingly becoming popular in agriculture and organic farming. In this book, the authors study and reveal their research on humic substances and the different aspects related to their formation. Other chapters include recent research on GRSP (Glomalin Related Soil Protein)…
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Quick ViewChlorpyrifos (CPF) is a broad spectrum organophosphate pesticide. Organophosphate pesticides comprise a group of substances used in agriculture for insect and plague control, infestations in buildings, man or domestic animals. The use of insecticides represents an environmental risk due to the high mass of product applied annually. This book discusses the toxicological properties, uses and…
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Quick ViewSalicylic acid (SA) and methyl jasmonate (MJ) signaling is associated with phospholipids and the enzymes that metabolize them. However, despite the many studies conducted, the role of SA or MJ signaling via phospholipids in plant responses is not yet fully understood. The signaling pathways of SA and MJ have been evaluated in plant cell suspensions,…
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Quick ViewEven though the ApoA5 gene was discovered more than 13 years ago by Pennacchio et al, 2001 [1], and it was known then the gene influences triglycerides, leading to speculations that it would affect the risk of stroke; the factors that affect cardiovascular diseases are very complex. Larry Baum’s group shown that APOA5 genotypes were…
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Quick ViewThe study on molecular rotors and motors is a hot research topic in the current era of nanotechnology. Internal rotation is a ubiquitous motion in most molecules and is considered a bridge to interconnect different energy forms. This monograph is focused on the computational studies on the molecular dynamics of the internal rotation of methyl,…
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Quick ViewLayered double hydroxides (LDHs) or hydrotalcites are inorganic clay materials with many promising properties. LDHs are a family of natural and synthetic compounds having the general formula [M(II) 1-x M(III)x (OH)2 ](Yn-) • yH2O, where M(II) and M(III) represent divalent and trivalent metal ions, respectively, and Yn- is the anion between the layers. They consist…
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Quick ViewThis book presents an overview of the role in biological processes and health effects produced by indoleamines, which are ubiquitous and versatile molecules with important physiological functions. The topics analyzed in this book cover a broad spectrum of functions played by indoleamines including the role of indoleamines in reducing free radical damage and oxidative stress;…
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Quick ViewThis book discusses a group of natural compounds that is referred to in many bibliographic references for its multiple medical and therapeutic applications, which have been carried out by civilizations in the past and continue to be used in the present. Thus, the alkaloids have been isolated from marine and terrestrial sources and human beings…
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Quick ViewIn the post-genomic era, science is still challenged to explain the biosynthesis of complex polysaccharides and glycoconjugates. Unlike nucleic acids and proteins, the information needed for their biosynthesis is not clearly contained to this day within the genome of the various organisms. This means that no biosynthetic code has been revealed yet. As a result,…
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Quick ViewHuman Serum Albumin (HSA) is the most abundant plasma protein. It has been widely used for drug delivery systems and has recently emerged as a versatile carrier for therapeutic agents against diabetes, cancer and infectious diseases. This book provides an overview of the expanding field of preclinical and clinical applications and developments that use albumin…
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Quick ViewThe genus Fusarium are among the most common contaminants of cereals and their products, and many species have acquired additional importance because they have been shown to produce mycotoxins (fumonisins), causing both animal and human diseases. Fusarium spp. molds and fumonisins were also found to be contaminants on various commodities around the world. The authors…
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Quick ViewCyclodextrins (CDs) are capable of interacting with a large variety of guest molecules to form inclusion complexes. The authors of the chapters that form this book discuss the development of ion-selective electrodes based on selected cyclodextrins and their derivatives as selective ionophores for various drugs and their applications in pharmaceutical research; the wide range of…
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Quick ViewEicosanoids constitute a large and expanding family of bioactive lipids synthesized from polyunsaturated fatty acids (PUFA) to either pro-inflammatory omega-6 arachidonic acid (AA) or anti-inflammatory omega-3 eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). In these last cases, two essential fatty acids (FAs) (ω-6 linoleic acid (C18:2n6) and ω-3 linolenic acid (LA) (C18:3n3) are utilized as…
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Quick ViewCirculating high-density lipoprotein (HDL) cholesterol (HDL-C) is a marker associated with cardiovascular health. Exercise is generally known to increase the HDL-C levels, and this can, in part, explain its cardioprotective effects. The authors present data regarding the association between exercise and the HDL quality and further encourages taking into consideration the view of HDL quality…
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Quick ViewMalondialdehyde (MDA) is one of the better-known secondary products of lipid peroxidation, and it can be used in biomaterials as an indicator of cell membrane injury. The first chapter offers an overview of the implications of MDA on oxidative stress, and therefore in neurogenerative diseases, as well as collects information of several natural products that…
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Quick ViewThe opening chapter of Phytochemicals: Plant Sources and Potential Health Benefits discusses macronutrients and micronutrients from plants along with their benefits to human health. An overview of the mechanisms of action underlying the potential roles of dietary soybean isoflavones including daidzein, genistein, and equol that may have benefits in dyslipidemia, ischemic heart disease, blood pressure,…
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Quick ViewThreonine, one of proteinogenic as well as essential amino acids, is classified as polar and uncharged residue, which may play an important role in intermolecular interactions between protein molecules and small ligand molecules. This book includes chapters on the lysozyme of egg white, which contains seven threonine residues in the primary structure; the requirements of…
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Quick ViewSphingolipids are involved in a wide range of physiological and pathological processes none only s signaling molecules but also as key structural components regulating the lateral organization of cellular membranes. In this book, exciting new approaches that open a window to further characterize sphingolipid-enriched domains in cell membranes during both physiological and pathological processes are…
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Quick ViewGibberellins (GA) are a large group of tetracyclic diterpenoid carboxylic acids, which are essential for many processes in plants, including seed germination. In combination with other hormones, it helps the plant to overcome abiotic stress. The authors of this book examine the main issues regarding the production, functions and biosynthesis of gibberellins. The importance of…
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Quick ViewLeucine is a branched-chain essential amino acid. It accounts for approximately one-fifth of the requirements for essential amino acids. Leucine facilitates insulin-stimulated glucose uptake and insulin signaling in skeletal muscle cells. This book includes chapters on the physiological roles of leucine and the effects of leucine supplementation; the syntheses, properties and applications of the main…
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Quick ViewTrichloroethylene (TCE) has historically been used for various cleaning and degreasing applications. Because of the human and environmental health effects associated with exposure to TCE, it has been the target of many state’s pollution prevention (P2) programs over the past decades. Many P2 assistance providers consider this field to be “conquered” and have moved on…
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Quick ViewPhospholipids are the main components of biological membranes. This book covers the production, properties and use of natural and synthetic phospholipids as drug delivery systems for therapeutic agents, including small drugs, peptides/proteins and nucleic acids. Also covered in this book are major recent findings that elucidate the biochemical features of polyphenol-phospholipid interactions and their influence…
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