Horizons in Cancer Research (Numbered Series)

This book presents original results on the leading edge of cancer research. Topics discussed include the risk factors, diagnosis and treatment options for glioblastoma; the biology of the interleukin-2 (il-2)-based immunotherapies in cancer and autoimmune disease; RNA interference for cancer therapeutics; melanoma progression to metastatic disease; proteins, polysaccharide-peptide complexes and polysaccharides with antiproliferative and anticancer…

This book presents original results on the leading edge of cancer research. Topics discussed include curcumin; diagnosis of thyroid cancers in the era of molecular medicine; xerostomia; the potential role of arsenic trioxide in the treatment of iodine non-avid thyroid cancer; causes of xerostomia in the cancer treatment; and an alternative for preparing the cancer…

This book presents original results on the leading edge of cancer research. Topics discussed include the emerging roles of the Sirtuin family in cancer; coping with pain in children with leukemia; chemotherapy induced peripheral neurotoxicity; historical evolution of conservative surgery of breast cancer; peripheral neuropathies especially in cancer patients; the important pitfalls in the diagnosis…

This book presents original results on the leading edge of cancer research. Lipomas are extremely common benign lesions, representing the most common softtissue tumor, with a wide spectrum of clinical presentations and imaging appearances. Several subtypes are described, ranging from lesions entirely composed of mature adipose tissue to tumors intimately associated with nonadipose tissue, to…

Horizons in Cancer Research. Volume 71 begins by reviewing the histopathological features of head and neck squamous cell carcinoma and its precursor lesions, risk factors for head and neck squamous cell carcinoma including viral infection, chemical carcinogenic and ethnic predisposition. New knowledge about major pathways and signaling is also presented. Next, the clinical development of…

This book presents original results on the leading edge of cancer research. Chapter One summarizes what is currently known regarding the epigenetic regulation of osteosarcoma pathways and oncogenes, as well as clinical trials of drugs that exert epigenetic regulation. Chapter Two critically discusses the role of ECM-dependent signaling in osteosarcoma progression. Chapter Three illustrates the…

This book presents original results on the leading edge of cancer research. Chapter One reviews microRNAs as a novel diagnostic and predictive biomarker in human cancer. Chapter Two discusses the deregulated expression and function of S100 proteins in cancer cells. Chapter Three studies the current management of nasopharyngeal carcinoma and future directions in clinical research.…

This book presents original results on the leading edge of cancer research. Chapter One provides a brief overview of the recent updates in the role of the laboratory in establishing the diagnosis, methods of disease monitoring and mechanisms that contribute to tyrosine kinase inhibitor (TKI) resistance for patients with chronic myeloid leukemia. Chapter Two reviews…

Horizons in Cancer Research. Volume 69 opens with a discussion on hypothetical mechanisms of the induction of NKreg cells in cancer and possible approaches to their abrogation, suggesting that for profound understanding of the problem of NKregs in the context of future target cancer immunotherapy, extensive clinical observations of NKreg cells should be carried out.…

Progression of colorectal cancer (CRC) is a main cause of its morbidity and mortality. CRC progression is characterized by increased growth of the primary carcinoma as well as lymphatic and haematogenic spread. The microenvironment of primary or circulating and disseminated tumor cells seems to be essential in all steps of the metastatic process of CRC.…