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Quick ViewNon-invasive ventilation (NIV) has shown, in the last two decades, to be an essential ventilatory management modality for treatment of patients with diverse etiologies of acute and chronic respiratory insufficiency, with significant favorable outcomes in terms of improvement in gas exchange, respiratory muscle fatigue, and dyspnea. NIV is an alternative to invasive mechanical ventilation, with…
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Quick ViewIn this book, authors review the current knowledge on acute lung injury (ALI). ALI/acute respiratory distress syndrome (ARDS) is characterized by diffuse alveolar damage, alveolar capillary leakage, lung edema, neutrophil-derived inflammation, and surfactant dysfunction. These changes lead to clinical manifestations of decreased lung compliance, severe hypoxemia, and bilateral pulmonary infiltrates. In the first chapter the…
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Quick ViewTracheostomy tubes provide a stable airway for ventilator support and allow access to the lower respiratory tract for secretion management. Indications for placement of a tracheostomy tube vary from relief of upper airway obstruction to ventilation for protracted acute respiratory failure to a chronic neuromuscular illness. This book focuses on the prospective practices, management, and…
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Quick ViewDespite the continuous effort from the scientific community and the advancements in neonatal intensive care, hypoxic-ischaemic brain injury of term and near-term infants remains a significant problem throughout the world. After asphyxia, infants may suffer from long-term neurological sequelae, including death, cerebral palsy, learning difficulties, epilepsy and other significant cognitive, developmental and behavioral problems in…
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Quick ViewChronic obstructive pulmonary disease (COPD) is a major cause of disability and is the fourth leading cause of death throughout the world. Although cigarette smoking is the major and best studied causative factor of COPD, there is consistent evidence that a substantial proportion of COPD cases cannot be explained by smoking. Other noxious particles and…
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Quick ViewChronic obstructive pulmonary disease (COPD) is a respiratory disorder characterized by chronic and recurrent air flow obstruction that increases resistance and dynamic hyperinflation of the peripheral airways. Chapter One presents a system for classification of COPD, based on fuzzy rules and a trained neural network. In Chapter Two, surrogate outcomes (i.e., physiological and/or anatomical outcomes)…
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Quick ViewSarcoidosis is a multisystem granulomatous disease of unknown etiology that is characterized by noncaseous epithelioid cell granulomas, which may affect almost any organ in the body. Intrathoracic involvement is common and accounts for most of the morbidity and mortality associated with this disease. The diagnosis is based on the total exclusion of other granulomatous disorders.…
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Quick ViewCurrently, positive pressure mechanical ventilation has gained widespread recognition as an essential strategy in the treatment of various forms of acute and chronic respiratory failure. Its mechanism impacts directly or indirectly on respiratory physiology (gas exchange) and/or respiratory musculature in various medical/surgical pathological conditions. In addition, positive pressure mechanical ventilation has been recognized as a…
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Quick ViewThe purpose of the book is to present up-to-date summary of the newly detected viruses and to guide clinicians and microbiologists to the relevant topics and help to make readers aware of the increasing problem of respiratory viruses. Although much is published on new respiratory viruses and its acceptance in having a daily impact in…
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Quick ViewCystic fibrosis (CF) is one of the most common autosomal recessive disorders in the Caucasian population with an estimated incidence of 1 in 2,500 childbirths. While this disease affects several organ systems of the body, morbidity and mortality is chiefly related to the extent of pulmonary involvement. Idiopathic pulmonary fibrosis (IPF) is the most common…
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Quick ViewThere is extensive literature available on pleural effusions and in recent years there has been significant developments in their diagnostic evaluation. The use of point of care ultrasound, pleural manometry, and medical pleuroscopy has expanded over the last decade. The goal of writing this book was to become a source or reference for clinicians who…
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