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Quick ViewAs one of the biological factors that most powerfully impacted history, infectious diseases continue to be a leading cause of global morbidity and mortality. At least two major factors are making infectious diseases assume more important roles than ever before. One of these is the increasing ability of certain microorganisms, normally limited to other species,…
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Quick ViewListeria monocytogenes is a foodborne pathogen transmitted to humans through ingested food. This bacterium is responsible for human listeriosis, an extremely serious infection with a high mortality rate. In Listeriosis Outbreaks: Symptoms, Risk Factors and Treatment, the authors study the symptoms, risk factors and treatment of human listeriosis. L. monocytogenes is more deadly than other…
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Quick ViewPeriodontal diseases are chronic infectious diseases characterized by a destructive inflammatory process affecting the supporting tissues of the tooth. Numerous bacterial species have been isolated from subgingival plaque, which are closely associated with disease onset and progression. At the same time, there is strong evidence that destructive processes occurring as part of the host inflammatory…
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Quick ViewEndophthalmitis refers to the inflammation of the intraocular tissues and fluids of the eye and can be non-infectious or caused by bacterial, fungal or parasitic infection. It can be classified as exogenous (post-operative, post-traumatic or as a complication of a corneal ulcer) or endogenous (secondary to hematogenous spread from another infected site). This book discusses…
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Quick ViewThe World Health Organization expects deaths from non-communicable diseases to rise by 15% between 2010 and 2020, with jumps of over 20% in Africa and South-East Asia. For example, the number of people in the developing world with diabetes will increase by more than 2.5-fold, from 84 million in 1995 to 228 million in 2025.…
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Quick ViewThe objective of the first chapter is to explain fertility preservation decisions as related to reproductive-aged cancer patients’ experiences and desires for future fertility. The second chapter discusses fertility preservation and how it can be used to help cancer patients retain their fertility. It is an emerging discipline that now plays a central role in…
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Quick ViewThe first section of this book discusses Clostridium difficile Infections (CDI). There is no consensus on the definition of severe CDI, since it varies depending on the authors or clinical practice guidelines consulted. Severe CDI can be defined as an episode of CDI with one or more specific signs and symptoms of severe colitis or…
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Quick ViewHuman African trypanosomiasis or sleeping sickness is caused by infection with the morphologically indistinguishable subspecies Trypanosoma brucei rhodesiense (in East and Southern Africa) and Trypanosoma brucei gambiense (in West and Central Africa). The disease is presently almost under control and less than 4000 cases are currently reported. In both, T. b. rhodesiense and T. b.…
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Quick ViewMeasles is a disease of public health importance that is associated with high morbidity and mortality particularly in developing countries. In recent years widespread application of measles vaccine among children has led to decline in morbidity and mortality attributed to measles. In the city of Gweru in Zimbabwe operations research was carried on the epidemiology…
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Quick ViewThis new book presents topical research in the study of E. coli infections, including urinary tract infections caused by E. coli; aptamer-based detection and therapeutics to prevent and treat E. coli infections; Lactoferrin as a novel natural host defense protein; enterotoxigenic escherichia coli colonization factors and the prevention of E. coli using organic acids. (Imprint:…
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Quick ViewPast communicable diseases, such as the recent Ebola epidemic, have resulted in many deaths and highlight the potential economic cost of disruptions to air travel and the U.S. and global economies. This book examines the extent to which selected U.S. airports and airlines have plans for responding to communicable disease threats from abroad and to…
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Quick ViewIn late 2015, health officials in Brazil recognized a marked increase in the number of infants born with microcephaly (from Greek, meaning “small head”), a birth defect that may accompany significant, permanent brain damage. Although not conclusive, the increase in microcephaly is suspected to be related to the emergence of Zika virus infections in Brazil…
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Quick ViewThe author was motivated to write this important book because currently there is no systematically-written document on the ZIKV disease, which could serve at this crucial moment as a textbook for medical students, physicians, nurses, and other healthcare providers as well as a reference book for basic researchers, professors, and the general public. The original…
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The bubonic plague, smallpox, HIV/AIDS, malaria, and influenza are some of the worst epidemics/pandemics that afflicted human beings from antiquity to modern times, killing millions of people. The mosquito-borne human-infecting viruses, rotavirus, and the seasonal influenza regularly affect lives across continents in the millions. Currently, we are facing various disease-inducing organisms of the Flavivirus family…
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Quick ViewToxoplasma gondii is an obligate intracellular parasite that infects 10-20% of the overall population in the US with rates increasing with age. T. gondii infects most warm blooded animals where an antibody response is generated to control the infection, however, the parasite forms bradyzoite cysts in brain and muscle. It can only reproduce in felines…
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Quick ViewSexually transmitted infections (STIs) represent a global problem that has an impact on the reproductive and sexual health worldwide. The most common causative agents of the STIs are Chlamydia trachomatis, Neisseria (N.) gonorrhoeae, Treponema pallidum and Trichomonas vaginalis. The World Health Organization estimated that these four main curable STIs cause approximately 498.9 million new cases…
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Quick ViewThe aim of this book is to clarify the epidemiologic aspects and control related to cryptosporidiosis in humans and domestic animals. Obligate intracellular parasites, the protozoa of the genus Cryptosporidium develop in the microvilli of the epithelial cells of the gastrointestinal tract, respiratory and urinary tracts of mammals, birds, reptiles and fish, and cause disease…
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Quick ViewThe Sub-Specialty Care of HIV-Infected Patients is a synthesis of current policies, practices, and recommendations regarding the management of HIV-infected patients, authored by academicians at two major Houston medical institutions, Baylor College of Medicine and the University of Texas at Houston. The chapters represent the traditional sub-specialties of internal medicine, with infectious disease represented in…
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Quick ViewIn Chagas Disease: Prevalence, Diagnosis and Treatment Options, the authors begin reviewing the characterization of American trypanosomiasis, or Chagas Disease, noting that although the disease has become less prevalent in recent decades, it is estimated that 8-10 million people are currently infected. Next, authors present a study wherein the dynamics of Trypanosoma cruzi infection (which…
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Quick ViewAutoimmune Myasthenia Gravis (MG) is mediated by pathogenic autoantibodies to components of the postsynaptic muscle endplate at the neuromuscular junction. Due to the clinical heterogeneity of the disease, there is a great need for objective biomarkers for diagnostic as well as therapeutic purposes. Humoral biomarkers of MG can be divided into two categories: 1) autoantibodies;…
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Quick ViewThe different anticoagulant drugs used both in the treatment and prevention of deep venous thrombosis can cause several adverse effects. The most significant complication is bleeding. In Advances in Health and Disease. Volume 6, the authors begin by examining how to choose the most appropriate drug for decreasing the risk of bleeding, taking into account…
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Quick ViewWith the knowledge that there are several pieces of information concerning the chemotherapy of trypanosomatids, it is important to put together the different aspects of this subject. This book is an updated version of several areas such as molecular biology, biochemistry, immune response to the studied compounds, pharmacology, etc. The chapters were written by experts…
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Quick ViewQ fever was first described in 1937 by Dr. Edward Holbrook Derrick among abbatoir workers in Queensland (Australia). This worldwide zoonotic disease caused by the bacterium Coxiella burnetii also affects several domestic and wild mammal species, birds and arthropods, which can serve as reservoirs. The transmission between or within populations mainly occurs via inhalation or…
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