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Quick ViewMeasles is still the cause of disease and even death around the world, and with the modern widespread travel around the globe, it can be spread from one site to another with ease. Rubella infection, especially during pregnancy, can also have important effects on the fetus and the family involved. The WHO African regional target…
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Quick ViewRegulatory T cells (Tregs) are a vital component of the T cell immune system by their ability to control T cell responses that would lead to autoimmune disease. Tregs also protect damaged normal cells that are healing from T cells programmed to kill any abnormal cells in the body. Cancer (tumor) develops from normal cells…
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Quick ViewPemphigus vulgaris (PV) is the most frequent condition inside the pemphigus group, especially in Europe and North America. It is the prototype of a genetically mediated disease. The HLA alleles associated with PV are well-known. Recent studies found an association between disease severity and some HLA DRB1 and DQB1 alleles. The author of this book…
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Quick ViewBehçet’s disease is a chronic relapsing inflammatory disease of unknown etiology involving multiple organs. Along with blindness, other bodily functions are greatly affected by this disease; conditions of the vascular, intestinal and central nervous systems are usually life threatening and require aggressive therapy. Recently, significant progress has been made in several areas of this disease.…
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Quick ViewSystemic lupus erythematosus (SLE or lupus) is a fairly common disease with a relatively high mortality rate that is characterized by multisystemic disorders, including the kidney. Recently, epidemiologic studies also show that the incidence of new SLE cases is increasing. Renal involvement is very common in systemic lupus erythematosus, occurring in up to 2/3 of…
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Quick ViewFood allergy is an inappropriate immune response to certain food components. Although its increasing prevalence over the past two decades and potentially fatal consequences have made food allergy a formidable public health issue, there has been no effective therapy to treat food allergy, and patients are compelled to resort to the strict avoidance of allergenic…
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Quick ViewFood allergies have a considerable impact on modern society. Some of the most severe allergic reactions occur when peanuts and peanut derivatives are consumed. The main causative agents of a peanut allergy are proteins. The total protein content of a peanut is represented by thirty-two different proteins, of which about eighteen (nearly 7-10%) have been…
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Quick ViewThis book provides research on the components, functions and diseases of the lymphatic system. Chapter One reviews the role of lymphatic drainage of cerebrospinal fluid from the brain. In particular, the authors review the current hypotheses on the possible drainage of lymphatic fluid from the brain. Chapter Two expose the actual refinements of the surgical…
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Quick ViewThis book provides an overview of the different topics of staphylococcal research in recent years. Severe infections caused by methicillin-resistant Staphylococcus aureus (MRSA) have become a global health problem in the twenty-first century. Chapter One discusses MRSA as a major cause of healthcare or hospital-associated infections (HA-MRSA) in burn patients, indicated as a high-risk group…
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Quick ViewThis book provides new research on immunosuppressives. Chapter One focuses on practical issues concerning immunosuppression in nephrology. Chapter Two discusses the global significance of hepatitis B virus (HBV) infection, the clinical scenarios in which immunosuppresive therapy may reactivate HBV, and different management strategies to prevent HBV reactivation. Chapter Three reviews the effect of immunosuppressive therapy…
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Quick ViewBeing diagnosed with Systemic Lupus Erythematosus (SLE) can be a severe disappointment, and life after diagnosis can be defined as an existence filled with uncertainty as to the short-and long-term impact of the disease. SLE is a chronic multi-system autoimmune disease that is persistent and recurrent and has the potential of becoming life threatening. The…
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Quick ViewThis book provides new research on types and roles of autoantibodies. Chapter One analyzes autoantibodies in diabetes. Chapter Two discusses the role of autoantibodies towards TNF in patients with rheumatoid arthritis and bronchial asthma. Chapter Three examines new findings on immunoglobulin E in eosinophilic granulomatosis with polyangiitis. (Imprint: Nova Biomedical)
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Quick ViewDirect immunofluorescence (DIF) microscopy on perilesional skin is still considered the gold standard for the diagnosis of BP. However, a rich armament of laboratory techniques is necessary for establishing an accurate diagnosis which, in its turn, is crucial for the choice of treatment modalities and determination of the disease prognosis. The disease is rarely diagnosed…
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Quick ViewHelper T Cells: Types, Functions and New Research presents current research in the Tfh cell research field with a special focus on the maintenance of TFH cells and their fate once the immune response has resolved. Whereas early steps of Tfh cell generation have been the subject of intense research in recent years, much less…
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Quick ViewThe opening chapter of Antiphospholipid Antibodies (APLA): Types and Functions in Health and Disease is focused on the modern immunoassays for the determination of aPL in biological fluids. The principles of these methods will be described and the possibility of their applications for aPL analysis will be mentioned. Next, the authors examine antiphospholipid syndrome (APS),…
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