Pediatric Cardiac Postoperative Handbook

Postoperative care of children with heart disease is a complex endeavor with plenty of opportunities for mishaps. Clinical teams taking care of these patients are usually comprised of physicians and nurses with very diverse background and experience. This Pediatric Cardiac Postoperative Handbook addresses the need to provide a concise and practical text for quick reference while at the same time covering the wide palette of issues a provider confronts while taking care of these patients. An ample range of topics is covered, from basic concepts of cardiopulmonary bypass and the resulting systemic response to specific postoperative management of patients with biventricular and single ventricle defects. We believe it will be a much valued resource for novel and experienced clinical providers in the pediatric CICU in the international setting. Dr. Torres Pacheco and the distinguished team at Hospital Beneficencia Portuguesa should be commended for this fantastic achievement. - Ricardo Munoz, MD, FAAP, FCCM, FACC, Chief, Division of Cardiac Critical Care Medicine, Co-Director, Children’s National Heart Institute, Children’s National Hospital and Alejandro Lopez-Magallon, MD, Senior Cardiologist, Division of Cardiac Critical Care Medicine, Children’s National Hospital

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Parasomnia Dreaming: Exploring Other Forms of Sleep Consciousness

"Parasomnia Dreaming is a fascinating and important book about the world of dreams emerging with abnormal sleep related behaviors and experiences - the parasomnias. Top experts contribute their research findings and valued clinical and neuroscience perspectives, along with perspectives from literature and the artistic creative process. The parasomnia dream reports will open many eyes and pique curiosity while setting the stage for this engrossing book." - Carlos H. Schenck, M.D., Professor, University of Minnesota Medical School, Author, Sleep: The Mysteries, The Problems and The Solutions

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Shyness Logophobia Mutism: Diagnosis and Therapy

“The work by Zbigniew Tarkowski and Ewa Humeniuk is devoted to mutism, a disorder that is heterogeneous in terms of its clinical manifestations and of even more complex etiology. The authors made an effort to examine the phenomena related to mutism that are complementary to it and partly explain its complexity. A great deal of the study is concerned with the notion of shyness and logophobia, the phenomena that outstandingly explain the genesis of mutism"...READ MORE - Professor Waldemar Tłokiński

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Vitamin D as Progesterone-Like Hormone: Novel Applications in Obstetrics and Gynecology

"This book summarizes in a transparent manner the most recent knowledge about the role of vitamin D in reproductive medicine. The authors focus, in individual chapters, on the explanation of the role played by vitamin D during the consecutive stages of pregnancy starting from conception. It is an excellent and innovative source of knowledge for anyone assisting patients with reproductive problems." - Artur Wdowiak Assoc. Prof., MD, Ph.D., Head of Diagnostic Techniques Unit, Medical University of Lublin, Poland

"This is a first review concerning the comparative analysis of the data about progesterone-like activity of Vitamin D in women. The book might help to understand a gap between the relationship of Vitamin D and progesterone physiological functions in human reproduction. I believe that this book gives an extensive biologic plausibility to the theory that vitamin D levels would be an effective target for fertility improvement and pregnancy outcomes. It appears that the chapter on vitamin D and its progesterone-like action for the general population may have been written based on the most recent trials. However, many questions still remain and will likely fuel ongoing investigation and debate. Are there benefits to vitamin D supplementation regarding fertility outcomes? What is the true benefit on pregnancy outcomes for vitamin D administration in the women population? These questions and others in both fertility and pregnancy will likely keep the book open on vitamin D for the foreseeable future." - Julia Fedotova, Professor, PhD, Department of Chemistry and Molecular Biology, ITMO University, St. Petersburg, Russia

"To date, Vitamin D is fully considered a secosteroid hormone, since it acts on several cellular mechanisms through both genomic and non-genomic pathways. Indeed, accumulating evidence suggests that both calcitriol and, its direct precursor, calcidiol, play a pivotal role to maintain metabolic, hormonal and immune homeostasis in different tissues and microenvironments in humans. In addition, several pieces of evidence support the paramount importance of Vitamin D compounds in human reproduction, both for male and female fertility as well as for several key events such as decidualization, oocyte developmental competence, embryo implantation, placental framework formation, and immune regulation at the maternal-fetal interface. In this scenario, this new book provides a comprehensive summary of the complex mechanisms orchestrated by Vitamin D, from the basic science to the clinical application. I think that this book could be considered a real milestone for gynecologists, obstetricians, endocrinologists, diabetologists and experts of reproductive medicine, since it can be truly helpful to guide the decision-making process in the clinical practice through an evidence-based approach." - Antonio Simone Laganà, M.D., Ph.D., Department of Obstetrics and Gynecology, “Filippo Del Ponte” Hospital, University of Insubria, Varese, Italy

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When Life Expectancy Is Falling: Mortality Crises in Post-Communist Countries in a Global Context

"Falling life expectancy is one of the most serious economic and social problems facing post-communist countries. This insightful book is a must-read for policymakers, researchers, and general readers interested in the causes and consequences of this mortality crisis. It also offers a number of concrete and specific policy directions for those countries to overcome their demographic challenge and more broadly, regain their economic and social vitality and dynamism." - Professor Donghyun Park, Principal Economist, Economic Research and Regional Cooperation Department, Asian Development Bank

"A profound comparative study on life expectancy and the complexity of factors influencing its changes, especially the cases of decline in some countries in an era when economic progress should extend lifetimes. With the intellectual lead of professor Vladimir Popov as the editor of the volume, the book provides unique insight into an issue that ought to be a matter of concern not only for social policymakers but of all accountable people interested in fundamental global affairs. After all, this is about life and death." - Professor Grzegorz W. Kolodko, Kozminski University, Warsaw; author of Whither the Word: The Political Economy of the Future

"A cornucopia of information and explanation concerning the relationship between economic policy and mortality, especially in Russia, China and India. A controversial but nevertheless valuable resource for evidence-based economic and social policy." - Michael Ellman, Emeritus professor University of Amsterdam

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Creativity in Occupational Therapy: Person, Process, Product

“One of a kind, fresh perspective on creativity! Creativity in Occupational Therapy: Person, Process, Product provides a comprehensive, evidence-based exploration of creativity. As a multi-dimensional concept, creativity is examined as both a personal characteristic and one that is critical to the occupational therapy process. Dr. Oven states, "Creativity can be found in the way we approach the world, reason, occupy ourselves, develop abilities, and prepare for the future." (p. 32). Numerous definitions and theories of creativity are extensively discussed based on current literature and Dr. Oven's research. The most significant contribution is Dr. Oven's broad consideration of the use of creativity in occupational therapy practice. She discusses the traditional use of creative occupations as a therapeutic modality which is supported in the World Health Organizations' (WHO) recent report providing evidence that participation in creative arts promotes physical and mental health and prevents ill health (Fancourt & Finn, 2019). A significant contribution, however, is Dr. Oven's expanded view of the importance of creativity in the therapeutic process for both the therapist and the client. For therapists, creativity promotes open-mindedness, original ideas, and the ability to solve problems. As a part of client-centered care, Dr. Oven acknowledges the importance of incorporating the client's creativity in therapy to promote successful outcomes. She also explores how features of the work environment can foster or hinder creativity in practice. The monograph closes with a synthesis of her original mixed methods research on factors influencing creativity in occupational therapy. In sum, Creativity in Occupational Therapy: Person, Process, Product provides a unique and valuable contribution to occupational therapy and the general public's understanding and use of creativity in daily life.” - Susan Bazyk, PhD, OTR/L, FAOTA, Professor Emerita, Occupational Therapy, Cleveland State University, USA

“The content of the present book is highly applicable to real life situations of occupational therapists and at the same time rather innovative, as it encroaches on one of the least researched fields in social and health sciences, on the occupational therapy process and the role of creativity in it. The key contribution of the book is the cutting-edge approach to the creativity of occupational therapists in the occupational therapy process from a theoretical and empirical perspective. The author discusses in depth the creative process of occupational therapist in occupational therapy treatment, and the factors that trigger creativity, influence its course, stimulate and / or hinder it. The book offers an overview of synthesized and pulled key concepts on creativity from a variety of sources to provide a comprehensive resource for scientists and practitioners in the field. To achieve that, the author draws on recent interdisciplinary theoretical backgrounds (philosophical, psychological, sociological, medical, occupational therapy), available in scientific and professional literature worldwide. Furthermore, the book presents research tools for a novel assessment of creativity in occupational therapy, which makes the book both, relevant and practical.” - Dr. Bojana Lobe, Assistant Professor, Faculty of Social Sciences, University of Ljubljana

“This manuscript is a timely, fresh and exciting read that addresses several critical questions in the field of occupational therapy that are connected with the human, its vulnerability, and the need for a purpose-filled existence as well as with our shared humanity that should mark the professional relationship between the therapist and the client. This humanistic approach can only be achieved by supporting the client’s abilities, initiating new possibilities and leaning on the creative potential of a therapist who is sensitive to the needs of others. READ MORE... - Dr. Zalka Drglin, National Institute of Public Health, Ljubljana, Slovenia

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Racecadotril: An Effective Anti-Diarrheal Drug

“Diarrhea, whose morbidity is still a non-solved problem, still creates a great deal of anxiety among parents who look for something to stop the disease as quickly as possible. Racecadotril fulfills all the characteristics that an ideal antidiarrheal drug should have, as described by Dr. Robert Edelman in 1985, when adequate antidiarrheal drugs were not yet available. Taken by mouth, racecadotril is rapidly absorbed in the intestine and found subsequently in large quantities in the submucosal structures of the intestinal wall. It inhibits the enkephalinase activity, protects enkephalins from inactivation, reduces cytosolic cyclic AMP level, and rapidly controls hypersecretion of water and electrolytes without affecting the intestinal motility. Furthermore, it does not cross the blood-brain barrier and thus has no sedative effects. This book, edited by Dr. Marco Manfredi, is a comprehensive review of racecadotril. A group of experts in the field reviews its history, pharmacologic properties, mode of action, and results of clinical trials conducted to prove its efficacy and safety. It is particularly remarkable to have among the authors, Dr. Schwartz and Dr. Lecomte, who were the developers of this drug. Time will prove that this book is an excellent addition to the bookshelf of those who have an interest in the field of diarrheal diseases and its treatment.” - Eduardo Salazar-Lindo, MD, Professor of Pediatrics, Universidad Peruana Cayetano Heredia

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Spinal Cord and Spinal Column Tumors

"Management of spinal cord and spinal column tumors has extended the reach of the neurosurgeon. This book reviews the main tumors of this area of the nervous system and gives an overview on the main approaches in a step-by-step fashion. The goal of this book is, therefore, to assist neurosurgeons and spinal surgeons to better understand the main neoplastic pathologies of this area, and limits and possibilities of spinal approaches. I am pretty sure that this volume will lead to improve the knowledge on spinal cord and spinal column tumors and their management for better care of patients." - Giovanni Grasso, MD, PhD, Associate Professor, Neurosurgical Clinic, Department of Experimental Biomedicine & Clinical Neurosciences, Deputy Rector for Relationships with Medical & Scientific Associations and Charities, University of Palermo, Italy

"Dr. Landi and Dr. Defini have edited a most comprehensive text on spinal cord and spinal column tumors. By starting with the basic anatomy and biochemistry, they lay the groundwork for a better understanding of all the following chapters. This approach is laudable. The topic is one of the most important in the field of neurosurgery. Spinal cord tumors are poorly understood, and often overlooked. Not since the book from Johns Hopkins Hospital "Surgery for Skull Base Tumors (Contemporary Issues in Neurological Surgery)" edited by Donlin Long, MD, PhD, has there been such a comprehensive text on these issues. According to the American Association of Neurological Surgeons, primary tumors arising from the spinal cord, spinal nerve roots and dura are rare compared to CNS tumors that arise in the brain. Overall prevalence is estimated at one spinal tumor for every four intracranial lesions. About 10,000 Americans develop primary (30%) or metastatic (70%) spinal cord tumors each year. This book, edited by Dr Landi and Dr. Defini brings new clarity of understanding of this rare, but potentially devastating clinical process. Any neurosurgeons will greatly benefit from this volume." - Nelson Hendler, MD, MS, Former assistant professor of neurosurgery, Johns Hopkins University School of Medicine, Former associate professor of physiology University of Maryland School of Dental Surgery

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Advances in Medicinal Chemistry Research

“This book covers hot current topics in medicinal chemistry, using a molecular-based approach, providing us with knowledge on new and valuable targets, on corresponding active synthetic and natural products, and deserves to be read by a broad audience, providing a rich food for thought." - Dr. Marilia O. Fonseca Goulart, Professor, Federal University of Alagoas – Brazil

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Type I Interferon in Autoimmune Diseases and its Clinical Applications

"This is an important and timely resource of type I interferons and their relationship to autoimmune disease. The book fist addresses the basic biology of interferon signaling and gives the reader a firm grasp of the molecular machinery operating both upstream and downstream of the interferons." READ MORE... - Dr. David Fiorentino, an Associate Professor of Dermatology at Stanford University School of Medicine

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